1-First Step: Prep and make the Cajun seasoning Measure out the spices to make the Cajun seasoning: 2 tsp smoked paprika, 1 tsp dried oregano, 1 tsp dried thyme, 1 tsp garlic powder, 1 tsp onion powder, 1/2 tsp cayenne pepper, 1/2 tsp black pepper, and 1/2 tsp salt. Mix them in a small bowl so the flavors are evenly distributed. Using this dry rub makes it easy to coat the chicken evenly and guarantees a consistent taste in every bite.

2-Second Step: Cut and season the chicken Trim and pat dry 1 lb (450g) boneless, skinless chicken breasts. Cut into roughly 1-inch cubes so they cook evenly and quickly. Toss the chicken cubes with the prepared Cajun seasoning until well coated. If you prefer milder heat, reduce the cayenne to 1/4 tsp or omit it entirely.

3-Third Step: Brown the chicken Heat 1 tbsp olive oil and 2 tbsp butter in a large deep skillet (use at least a 4-quart capacity) over medium-high heat until the oil is hot and butter is foamy. Add the seasoned chicken in a single layer and cook about 3 to 4 minutes on each side. You’re aiming for a nice brown crust but not fully cooked through; the chicken will finish cooking with the pasta. Browning adds flavor through caramelization, so don’t rush this step.

4-Fourth Step: Sauté the onion Push the chicken to one side and add the diced medium yellow onion to the pan, or remove the chicken briefly if your skillet is crowded. Sauté the onion for 2 to 3 minutes until softened and translucent, scraping up browned bits from the bottom of the skillet with a wooden spoon. Those browned bits carry concentrated flavor into the sauce.

5-Fifth Step: Add pasta, tomatoes, and broth Add the uncooked 12 oz (340g) penne pasta, the full 14.5 oz (411g) can of fire-roasted diced tomatoes with their juices, and 2 cups (480ml) chicken broth to the skillet. Stir well to combine and make sure the pasta is mostly submerged. Cover the pan with a lid. Turn the heat up to bring the mixture to a boil, then reduce to medium-low to maintain a simmer. Cooking time will be about 10 to 12 minutes. Stir occasionally to prevent sticking and to check the pasta for doneness. Timing may vary a minute or two depending on your stove and skillet; aim for al dente pasta.

6-Sixth Step: Finish with cream cheese Once the pasta is tender and the sauce has thickened, remove the lid and stir in 4 oz (113g) cream cheese cut into chunks. Stir continuously until the cream cheese is fully melted and the sauce is creamy and smooth. If you prefer a looser sauce, add a splash more broth or a little reserved pasta water. For a dairy-free finish, use coconut milk or cashew cream here instead.

7-Final Step: Garnish and serve Top the finished One Pot Creamy Cajun Chicken Pasta with 2 thinly sliced green onions and serve immediately. A sprinkle of grated Parmesan or a crumble of cooked bacon makes a nice optional garnish if you’re adding extra toppings. This recipe serves 4 and pairs well with a simple green salad or garlic bread.